Resources

Reports

• Formative Research on Key Child Survival and Nutrition Practices in the First 1,000 Days of Life: Findings. Click here for the full report

Publications

Consulting: Quality, Research, Service Delivery, Health Systems Strengthening

1. Remote Facilitation of Essential Newborn Care: A Multinational, Multicenter Pilot Study. This pilot study in Nigeria and Bangladesh tested a hybrid training model for newborn care, combining online learning with frequent hands-on practice. Over 230 healthcare workers showed significant improvements in knowledge, resuscitation skills, and sustained competence, highlighting the model’s potential to strengthen newborn care in resource-limited settings.   https://doi.org/10.1542/pedsos.2024-000356
2. Breastfeeding Is Not the Sole Responsibility of Women’: A Qualitative Examination of the Supportive Environment for Breastfeeding in Nigeria Across Levels of the Socioecological Model. This qualitative study explores how breastfeeding in Nigeria is influenced not only by mothers but also by family elders, community norms, and the accessibility and quality of health services, revealing critical socioecological drivers and barriers. It underscores the need for multilevel, multicomponent interventions that extend beyond the individual to strengthen the enabling environment for breastfeeding.  https://doi.org/10.1111/mcn.70050
3. Enhancing private healthcare effectiveness in Lagos State, Nigeria: An overview of the effect of quality improvement initiatives and implications for sustainable healthcare delivery. This study examines donor-supported quality improvement programs in private facilities, showing better staff management, patient care, and reputational gains, though financial and systemic barriers limited patient inflow. It highlights the need for sustained partnerships and stronger links to health insurance for lasting impact. https://doi.org/10.4236/health.2024.162009
4. Gendered social norms, exceptions, and sanctions: Implications for maternal, infant, and young child nutrition in Nigeria. This qualitative study across the six geopolitical zones in Nigeria uncovers three deeply embedded gender meta‑norms around women’s mobility, household roles, and decision‑making that restrict engagement in maternal and child nutrition behaviors like food procurement and health care. The findings highlight crucial entry points for interventions that explicitly address gender inequities to bolster nutrition outcomes. https://cdn.nutrition.org/article/S2475-2991(24)02458-2/fulltext
5. Evaluating the effectiveness of quality improvement strategies in mid-level private healthcare facilities of Lagos State: A Donabedian model-based approach. Using a before-and-after design guided by the Donabedian model, this study shows that a 10–12 month quality improvement intervention lifted overall QI scores from 69% to 74%, improving infrastructure, processes, and patient satisfaction, though gaps remain in key services like family planning and labs. https://www.researchgate.net/publication/378452956_

Clinical Research: Observational Studies, Systematic Reviews, Trials

• Exploring the role of cervicovaginal microbiota as risk factor for cervical cancer in Sub-Saharan Africa: a systematic review and meta-analysis. This systematic review and meta-analysis across 15 studies found that cervicovaginal pathogens, such as Porphyromonas, Prevotella, Trichomonas vaginalis, alongside high-risk HPV and HIV infections, significantly elevate cervical cancer risk in Sub‑Saharan Africa. The findings point to the urgent need for integrated strategies combining microbiota management, sexual health education, and HPV vaccination. doi: 10.1186/s12905-025-03688-1.
• A systematic review and meta-analysis on the prevalence of extended-spectrum beta-lactamase-producing Klebsiella pneumonia in Nigeria. This meta-analysis of 18 studies found a pooled prevalence of approximately 47% for extended‑spectrum beta‑lactamase, producing Klebsiella pneumoniae (ESBL‑KP) in Nigeria, with OXA, TEM, and CTX-M as the most common resistance genes. The findings strongly advocate for enhanced antimicrobial stewardship and robust infection control measures in Nigerian healthcare settings. http://dx.doi.org/10.4314/ahs.v24i3.5
• Anti-biofilm, drug delivery and cytotoxicity properties of dendrimers. ADMET & DMPK. This review highlights dendrimers as advanced nanocarriers with properties such as multivalency, high solubility, non‑immunogenicity, and biocompatibility that enhance antimicrobial delivery and help dismantle biofilms. It outlines current applications and limitations, offering insight into their potential as next-generation anti-infective platforms. https://doi.org/10.5599/admet.1917.
• Occurrence of false positive tests and cross-reactions between Covid-19 and Dengue with implications during diagnosis: a mixed evidence synthesis. This mixed‑evidence synthesis reveals that both dengue‑positive patients (12.5%) and COVID‑19‑positive individuals (10%) frequently produced false‑positive results when tested with each other’s serological assays, leading to misdiagnosis and potentially inappropriate management in tropical settings. The study urges clinicians to interpret rapid serology with caution and adopt integrated diagnostic strategies to accurately triage febrile illnesses in areas where both infections co‑circulate. DOI: 10.1097/IM9.0000000000000116
• A meta-analysis on the prevalence of resistance of Staphylococcus aureus to different antibiotics in Nigeria. This comprehensive meta-analysis of 98 studies found alarmingly high resistance rates up to 82% among S. aureus isolates against commonly used antibiotics like penicillin G, cloxacillin, and amoxicillin-clavulanic acid, while resistance to ofloxacin, rifampicin, and vancomycin was notably lower (around 24%, 24%, and 13%, respectively).  The findings underscore the urgent need for stronger antimicrobial stewardship, enhanced infection control, and rational antibiotic use across Nigerian healthcare settings.  doi.org/10.1186/s13756-023-01243-x
• A review on Azadirachta indica (neem) plant mediated biosynthesis, characterization and antimicrobial activity of silver nanoparticles. This review covers the plant-mediated (green) biosynthesis, characterization, and antimicrobial activity of silver nanoparticles derived from Azadirachta indica, highlighting neem extracts as efficient, eco-friendly reducing and stabilizing agents. It underscores the therapeutic potential of these silver nanoparticles for antimicrobial applications. DOI:1504/IJBNN.2023.10060076
• A systematic review on anti-tuberculosis drug discovery and antimycobacterial potential of biologically synthesized silver nanoparticles: overview and future perspectives. This systematic review explores the antimycobacterial potential of biologically synthesized silver nanoparticles (AgNPs), demonstrating their promising efficacy against Mycobacterium species and suggesting new avenues for tuberculosis drug development. It highlights the need for further research into the mechanisms, safety, and scalable production of these green-synthesized nanotherapeutics. Doi: 10.1097/IM9.0000000000000107.
• Synthesis of silver nanoparticles using Nigella sativa seed extract and its efficacy against some multidrug-resistant uropathogens. This study reports a green synthesis of silver nanoparticles (AgNPs) using Nigella sativa seed extract and demonstrates their strong antimicrobial activity against multidrug‑resistant urinary tract infection pathogens. The findings highlight the potential of these biosynthesized AgNPs as eco-friendly alternatives for combating antimicrobial resistance in uropathogens.  Doi: 10.4103/bbrj.bbrj_104_22.

Community Services: Mental Health

1. Exploring the characteristics of callers of mental health emergency hotlines in Nigeria: A descriptive study. This descriptive study examined 717 calls to mental health hotline from across Nigeria from March 2022 to September 2023, finding that 71% were related to mental health concerns and came from all six geopolitical zones, most frequently from the South‑West and South‑South regions. Callers were more often male, but in the North‑East and North‑Central zones, female callers predominated, highlighting geographic and gender-based differences in help-seeking patterns. https://doi.org/10.11604/pamj-cm.2024.14.27.42375
2. Exploring sociodemographic predictors of suicide ideation and attempts: Insights from a mental health emergency hotline data. This study of 512 mental health–related hotline calls in Nigeria (March 2022–September 2023) found that 43% involved suicide ideation and 11.7% involved suicide attempts. It reveals that younger age and being separated/divorced reduced ideation risk, while being married and identifying as Christian were associated with lower odds of attempts. https://iannajournalofinterdisciplinarystudies.com/index.php/1/article/view/290
3. Situation report on suicide in Nigeria. This report highlights rising suicide trends in Nigeria, climbing from 6.5 per 100,000 in 2012 to nearly 9.9 in 2015, with prevalent methods including pesticide ingestion, hanging, and drowning. It underscores alarming gaps in surveillance, mental health infrastructure, and funding, advocating for systemic solutions like improved data systems, community-based services, and integration into primary health care. http://www.ajpssi.org/index.php/ajpssi/article/view/421

REACH Nembe Documentary

SafeZone – InSight School Health and Safety Initiative

Increasing Access to Family Planning and MNCH Services